With every day that passed he became ever more despairing.
隨著日子一天天過去，他越來越絕望。
One harsh word would send her into the depths of despair.
一句嚴厲的話就會使她陷入極度的絕望之中。
Don't despair! We'll think of a way out of this.
別灰心！我們會找到出路的。
The book describes a spiritual journey from despair to happiness.
這本書描述了從絕望到高興的心理變化過程。
They'd almost despaired of ever having children.
他們對生孩子幾乎不抱任何希望了。